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When you say you combined several segments into one, do you mean that you used Path menu > Combine?
Even though you've made one compound path, with several sub-paths, you still have to connect the nodes, to be able to fill it properly. Here's how to connect the nodes.
If 2 end nodes are on top of each other, you can select both by dragging a small selection box around them, with the Node tool. If they aren't on top of each other, you can select one at a time, while holding the Shift key, to end up with both selected.
Then click "Join selected nodes" button on the Node tool control bar. It looks like this
Or else there's a key shortcut, which you can find at Help menu > Key and Mouse Reference.
You'll need to closely inspect all the paths (with Node tool), to make sure thay are all connected.