Inkscape has a still relatively new feature, Snap Perpendicular, which sounds like it should be helpful. However, I can't seem to figure out how to use it. (I know how to enable it in Document Properties. But I don't see how to set one line perpendicular to another.)
Just to be clear, you don't know exactly where the new path will meet the line which the arrow is pointing to, at 90°. Right? But you know it needs to start at a particular node on the other line.
Well, maybe someone else knows how to use that snap feature. But meanwhile, I think this is how I would do it.
1 - duplicate the line with the arrow pointing to it
2 - move it away (just for clarity, but not absolutely necessary)
3 - with Selection tool, click a 2nd time on it, to reveal the rotation center and rotation arrows
4 - grab the rotation center and drag it towards one end of the path, and snap it to the end (let me know if you need help setting up snapping)
5 - drag it back over to where it came from, and snap the end with the rotation center to the original line - just snap it anywhere for now
6 - It's a little tricky to do this without using Object menu > Transform > Rotate, but it's possible. As you rotate, watch the status bar and you can see the degrees. Then just stop at 90°. But if that's too tedious, you can use the Transform dialog, Rotate tab, and set for 90°, then click Apply.
7 - Now the line is at the proper angle. So now you can snap the other end of it to the appropriate node, and it will intersect the original line at 90°
8 - However, the line is too long. Using the Selection tool, grab the corner arrow at the top-left, hold the Ctrl key down, and drag it shorter. If you have Snap to Paths button enabled on the snap control bar, the end should snap to that path.
I could make a video if that would be easier for you.
Is it going to be a tangram?