Hi.
It's not really a problem one can give the ultimate solution.
For the labeling, use the text tool (F8, for text settings Shift+Ctrl+T).
For setting fill and stroke styles in general, use the fill and stroke panel (Shift+Ctrl+F).
Most of the drawing will consist of paths with no fill but a black stroke, and maybe two markers.
Things can get more complicated if you are after specific needs like a custom arrowhead marker or a custom dasharray. I would go for those as well but that's not necessary to draw that image.
Frankly the only two parts I can think may need help is drawing a cylinder or drawing a helix.
The first can be drawn from an ellipse with the motion or extrude extensions or even manually in a few clicks (I'd use the polygon tool for this and manual construction).
For drawing the helix I'd use the parametric curves extension, like in this image:
-click on it for more details and svg source.
Which part got you stuck?